Common Early SymptomsIn the early stages, amyloidosis symptoms are often vague and easily overlooked. Common early signs include persistent fatigue, unexplained weight loss, swelling in the legs or ankles, and shortness of breath. Because these symptoms overlap with many other conditions, diagnosis is often delayed.

Organ-Specific Warning SignsAs amyloidosis progresses, symptoms may vary depending on the affected organs. Heart involvement may cause irregular heartbeat or heart failure symptoms, kidney involvement can lead to protein in the urine or swelling, and nerve damage may result in numbness, tingling, or carpal tunnel syndrome. Digestive symptoms such as diarrhea or early fullness are also possible.

When to Seek Medical EvaluationEarly recognition of amyloidosis symptoms allows patients to seek specialist evaluation and explore appropriate treatment options sooner. If symptoms persist or worsen without a clear explanation, consulting a healthcare professional for further testing may help protect long-term health.